Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Oxymetazoline Hydrochloride
Oxymetazoline Hydrochloride is an α2-Adrenergic receptor agonist. Enhances EGF- and PDGF-induced DNA synthesis.
MilliporeSigma™ Calbiochem™ Memantine Hydrochloride
Memantine Hydrochloride is a very potent, voltage-dependent, rapidly unbinding antagonist (calcium channel blocker) of NMDA receptors.
MilliporeSigma™ Calbiochem™ Juglone
A highly selective cell-permeable, irreversible inhibitor of PPlases (peptidyl-prolyl cis/trans isomerases of the parvulin family).
MilliporeSigma™ Calbiochem™ Caspase-1/4 Inhibitor, VX-765
A cell-permeable prodrug that upon conversion to its active form inhibits caspase-1 and 4 activity (Ki = 800 pM and 600 pM, respectively).
MilliporeSigma™ Calbiochem™ CBFβ Activator, Kartogenin
The CBFβ Activator, Kartogenin modulates the biological activity of CBFβ. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Dynamin Inhibitor III, Phthaladyn-23
A cell-permeable phthalimide compound that is reported to inhibit dynamin GTPase activity (IC50 =
MilliporeSigma™ Calbiochem™ Diaphanous (mDia)-related Formin Agonist, IMM01
An agonist of mammalian Diaphanous (mDia)-related formins that disrupts diaphanous inhibitory domain (DID) and diaphanous autoregulatory domain (DAD) interaction (IC50 = 140 nM).
MilliporeSigma™ Calbiochem™ Akt Inhibitor
The Akt Inhibitor controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NAE Inhibitor, MLN4924
NAE Inhibitor, MLN4924, CAS 951950-33-7, is an AMP mimetic that forms a NAE-catalyzed NEDD8 adduct, which acts as a tight-binding, ATP-competitive NAE inhibitor (IC50 = 4.7nM).
MilliporeSigma™ Calbiochem™ MitoBloCK-6
A cell-permeable, stable dichlorosalicylaldehyde Schiff's base that acts as a potent, selective inhibitor of Mia40/Erv1 redox-mediated import pathway (IC50 = 700 nM, 900 nM, an
MilliporeSigma™ Calbiochem™ (+/-)-Clopidogrel Hydrogensulfate
A thienopyridine compound that acts as a specific irreversible inhibitor of purinergic P2Y12 recept
MilliporeSigma™ Calbiochem™ KB-R7943
A cell-permeable isothiourea derivative that inhibits the influx/reverse mode of Na+/Ca2+ exchangers (NCX; IC50
MilliporeSigma™ Calbiochem™ MMP-2/MMP-9 Inhibitor IV
The MMP-2/MMP-9 Inhibitor IV, also referenced under CAS 292605-14-2, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.